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RAPGEF5 (9A5) Rabbit Monoclonal Antibody
RAPGEF5 (9A5) Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, FC, ICC |
|---|---|
| Primary Accession | Q92565, Q8C0Q9, P83900 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Dilution | WB~~1:1000 IHC~~1:100~500 IF~~1:50~200 FC~~1:10~50 ICC~~N/A |
|---|---|
| Storage Conditions | -20℃ |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
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