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PPA2 (6W7) Mouse Monoclonal antibody
PPA2 (6W7) Mouse Monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9H2U2 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Calculated MW | 37920 Da |
| Gene ID | 27068 |
|---|---|
| Other Names | Inorganic pyrophosphatase 2, mitochondrial, 3.6.1.1, Pyrophosphatase SID6-306, Pyrophosphate phospho-hydrolase 2, PPase 2, PPA2 |
| Dilution | WB~~1:1000 IHC~~1:100~500 |
| Storage Conditions | -20℃ |
| Name | PPA2 |
|---|---|
| Function | Hydrolyzes inorganic pyrophosphate (PubMed:27523597). This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function (PubMed:27523598). |
| Cellular Location | Mitochondrion. |
| Tissue Location | Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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