|Application ||WB, E|
|Other Accession||B0BNI5, Q8BK62|
|Calculated MW||46010 Da|
|Antigen Region||107-134 aa|
|Other Names||Olfactomedin-like protein 3, HNOEL-iso, hOLF44, OLFML3|
|Target/Specificity||This OLFML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human OLFML3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OLFML3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.|
|Tissue Location||Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Fautsch, M.P., et al. Exp. Eye Res. 82(6):1046-1052(2006)
Zeng, L.C., et al. FEBS Lett. 571 (1-3), 74-80 (2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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