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ADAMTS1 Rabbit pAb
ADAMTS1 Rabbit pAb
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P97857 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 105801 Da |
| Gene ID | 11504 |
|---|---|
| Other Names | A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS-1, 3.4.24.-, Adamts1 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | Adamts1 |
|---|---|
| Function | Cleaves aggrecan, a cartilage proteoglycan, at the '1691- Glu-|-Leu-1692' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity). |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
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Background
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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