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Recombinant Anti-GLUT1 Rabbit mAb
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P11166 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Calculated MW | 54084 Da |
| Antigen Region | Recombinant fusion protein of human GLUT1. aa |
| Gene ID | 6513 |
|---|---|
| Other Names | GLUT1; Solute carrier family 2, facilitated glucose transporter member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter |
| Dilution | WB~~1:500 - 1:1000 IHC~~1:100~500 |
| Format | The antibody was purified by immunogen affinity chromatography. iquid in PBS, pH 7.3, 50% glycerol, and 0.05% Proclin300. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SLC2A1 (HGNC:11005) |
|---|---|
| Function | Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:10227690, PubMed:10954735, PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:32860739). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed:18245775, PubMed:19449892). Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy- independent, facilitative transport of glucose into the brain (PubMed:10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity). Required for mesendoderm differentiation (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Melanosome. Photoreceptor inner segment {ECO:0000250|UniProtKB:P17809}. Note=Localizes primarily at the cell surface (PubMed:18245775, PubMed:19449892, PubMed:23219802, PubMed:24847886, PubMed:25982116). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) |
| Tissue Location | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues |
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Cat# AP94847
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