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FAM5C Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FAM5C Antibody (N-term) AP9487a
    Western blot analysis of FAM5C Antibody (N-term) (Cat. #AP9487a) in K562 cell line lysates (35ug/lane). FAM5C (arrow) was detected using the purified Pab.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q76B58
Other Accession Q8K1M7, Q499E0
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 88445 Da
Antigen Region 40-68 aa
Additional Information
Gene ID 339479
Other Names BMP/retinoic acid-inducible neural-specific protein 3, DBCCR1-like protein 1, BRINP3, DBCCR1L, DBCCR1L1, FAM5C
Target/Specificity This FAM5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human FAM5C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFAM5C Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BRINP3
Synonyms DBCCR1L, DBCCR1L1, FAM5C
Function Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.
Cellular Location Secreted. Mitochondrion
Tissue Location Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC) Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues
Research Areas
Citations (0)
citation

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References

Kuroiwa, T., et al. Oncol. Rep. 22(5):1005-1011(2009)
Connelly, J.J., et al. BMC Med. Genet. 9, 33 (2008)
Shorts-Cary, L., et al. Endocrinology 148(3):967-975(2007)

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$ 365.00
$ 140.00
Cat# AP9487a
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