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NUCKS1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q9H1E3 |
| Other Accession | NP_073568 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27296 Da |
| Antigen Region | 45-73 aa |
| Gene ID | 64710 |
|---|---|
| Other Names | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1, P1, NUCKS1, NUCKS |
| Target/Specificity | This NUCKS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human NUCKS1. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NUCKS1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NUCKS1 {ECO:0000303|PubMed:26323318, ECO:0000312|HGNC:HGNC:29923} |
|---|---|
| Function | Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR) (PubMed:26323318). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D- loop structures, but with less affinity than RAD51AP1 (PubMed:26323318). |
| Cellular Location | Nucleus. Chromosome |
| Tissue Location | Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Satake, W., et al. Nat. Genet. 41(12):1303-1307(2009)
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Wisniewski, J.R., et al. Proteins 73(3):710-718(2008)
Grundt, K., et al. Biochim. Biophys. Acta 1773(9):1398-1406(2007)
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