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NCOA7 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q8NI08 |
| Other Accession | Q6DFV7 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 106162 Da |
| Antigen Region | 76-103 aa |
| Gene ID | 135112 |
|---|---|
| Other Names | Nuclear receptor coactivator 7, 140 kDa estrogen receptor-associated protein, Estrogen nuclear receptor coactivator 1, NCOA7, ERAP140, ESNA1 |
| Target/Specificity | This NCOA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-103 amino acids from the N-terminal region of human NCOA7. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NCOA7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NCOA7 |
|---|---|
| Synonyms | ERAP140, ESNA1 |
| Function | Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA. |
| Cellular Location | Nucleus. |
| Tissue Location | Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
NCOA7 enhances the transcriptional activities of several nuclear receptors. It is involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.
References
?Arai, H., et al. Oncol. Rep. 19(6):1381-1388(2008)
?Liu, Y., et al. Schizophr. Res. 89 (1-3), 360-361 (2007) :
?Durand, M., et al. BMC Cell Biol. 8, 13 (2007) :
?Mungall, A.J., et al. Nature 425(6960):805-811(2003)
?Ohira, M., et al. Cancer Lett. 197 (1-2), 63-68 (2003) :
?Rushing, S.R., et al. Arch. Biochem. Biophys. 403(2):189-201(2002)
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