|Application ||WB, E|
|Calculated MW||21008 Da|
|Antigen Region||139-168 aa|
|Other Names||Gamma-glutamylcyclotransferase, Cytochrome c-releasing factor 21, GGCT, C7orf24, CRF21|
|Target/Specificity||This GGCT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the C-terminal region of human GGCT.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GGCT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GGCT (EC 220.127.116.11) catalyzes the formation of 5-oxoproline (pyroglutamic acid) from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis.
Oakley, A.J., et al. J. Biol. Chem. 283(32):22031-22042(2008)
Bae, E., et al. Proteins 70(2):588-591(2008)
Masuda, Y., et al. Biochem. Biophys. Res. Commun. 346(2):454-460(2006)
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