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ZN473 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q8WTR7 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 100182 Da |
| Antigen Region | 178-207 aa |
| Gene ID | 25888 |
|---|---|
| Other Names | Zinc finger protein 473, Zinc finger protein 100 homolog, Zfp-100, ZNF473, KIAA1141, ZFP100 |
| Target/Specificity | This ZN473 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the N-terminal region of human ZN473. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZN473 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZNF473 |
|---|---|
| Synonyms | KIAA1141, ZFP100 |
| Function | Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. |
| Cellular Location | Nucleus. Note=Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA |
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Wagner, E.J., et al. Mol. Cell. Biol. 26(17):6702-6712(2006)
Wagner, E.J., et al. RNA 12(7):1206-1218(2006)
Pillai, R.S., et al. Genes Dev. 17(18):2321-2333(2003)
Dominski, Z., et al. Genes Dev. 16(1):58-71(2002)
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$ 150.00
$ 385.00
Cat# AP9752a
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