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GNRH2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | O43555 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 12918 Da |
| Antigen Region | 26-53 aa |
| Gene ID | 2797 |
|---|---|
| Other Names | Progonadoliberin-2, Progonadoliberin II, Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, GnRH II, Luliberin II, Luteinizing hormone-releasing hormone II, LH-RH II, GnRH-associated peptide 2, GnRH-associated peptide II, GNRH2 |
| Target/Specificity | This GNRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the Central region of human GNRH2. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GNRH2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GNRH2 |
|---|---|
| Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. |
| Cellular Location | Secreted. |
| Tissue Location | Midbrain; expressed at significantly higher levels outside the brain (up to 30-fold), particularly in the kidney, bone marrow and prostate |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones.
References
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Poon, S.L., et al. Mol. Endocrinol. 23(10):1646-1656(2009)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)
Poon, S.L., et al. Endocrinology 149(10):5162-5171(2008)
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