|Application ||FC, IHC-P, WB, E|
|Calculated MW||34006 Da|
|Antigen Region||33-62 aa|
|Other Names||Phosphoglycolate phosphatase, PGP, PGPase, PGP|
|Target/Specificity||This PGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human PGP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PGP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).|
|Tissue Location||Detected in all tissues including red cells, lymphocytes and cultured fibroblasts (at protein level). The highest activities occur in skeletal muscle and cardiac muscle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Garcia, M.G., et al. Leuk. Res. 33(2):288-296(2009)
Lin, Y.C., et al. Ther Drug Monit 28(5):668-672(2006)
de Leon, J., et al. J Clin Psychopharmacol 25(5):448-456(2005)
Turzanski, J., et al. Exp. Hematol. 33(1):62-72(2005)
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