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Anti-CALCRL / CGRPR Reference Antibody (erenumab)

Recombinant Antibody

     
  •  - Anti-CALCRL / CGRPR Reference Antibody (erenumab) APR10013
    Anti-CALCRL / CGRPR Reference Antibody (erenumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-CALCRL / CGRPR Reference Antibody (erenumab) APR10013
    The purity of Anti-CALCRL / CGRPR Reference Antibody (erenumab)is more than 99.43% ,determined by SEC-HPLC.
    detail
  •  - Anti-CALCRL / CGRPR Reference Antibody (erenumab) APR10013
    Immobilized human CGRPR VLP Protein at 16 µg/mL can bind Anti-CALCRL / CGRPR Reference Antibody (erenumab),EC50=0.0206 µg/mL.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession Q16602
Reactivity Cynomolgus, Human
Clonality Monoclonal
Isotype IgG2SA
Calculated MW 146.2 KDa
Additional Information
Target/Specificity CALCRL / CGRPR
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name CALCRL (HGNC:16709)
Synonyms CGRPR
Function Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:22102369, PubMed:30115739).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Predominantly expressed in the lung and heart.
Research Areas
Citations (0)
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$ 365.00
Cat# APR10013
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