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Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv)

Recombinant Antibody

     
  •  - Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv) APR10057
    Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv) APR10057
    The purity of Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv)is more than 100% ,determined by SEC-HPLC.
    detail
  •  - Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv) APR10057
    Immobilized human NECTIN 4 His at 2 µg/mL can bind Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv),EC50=0.003846 µg/mL
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession Q96NY8
Reactivity Cynomolgus, Human, Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 143.9 KDa
Additional Information
Target/Specificity Nectin-4
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation MMAE
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name NECTIN4 (HGNC:19688)
Synonyms LNIR, PRR4, PVRL4
Function Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction. Note=Colocalizes with AFDN at cadherin- based adherens junctions (PubMed:11544254)
Tissue Location Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma
Research Areas
Citations (0)
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$ 365.00
Cat# APR10057
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