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Anti-TPBG Reference Antibody (PF-06263507)

Recombinant Antibody

     
  •  - Anti-TPBG Reference Antibody (PF-06263507) APR10069
    Anti-TPBG Reference Antibody (PF-06263507) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-TPBG Reference Antibody (PF-06263507) APR10069
    The purity of Anti-TPBG Reference Antibody (PF-06263507)is more than 99.25% ,determined by SEC-HPLC.
    detail
  •  - Anti-TPBG Reference Antibody (PF-06263507) APR10069
    Immobilized human 5T4 His at 2 µg/mL can bind Anti-TPBG Reference Antibody (PF-06263507),EC50=0.004604 µg/mL
    detail
  •  - Anti-TPBG Reference Antibody (PF-06263507) APR10069
    Human 5T4 HEK293 cells were stained with Anti-TPBG Reference Antibody (PF-06263507) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC121=0.7286 ug/Ml
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession Q13641
Reactivity Cynomolgus, Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 145.8 KDa
Additional Information
Target/Specificity TPBG
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name TPBG
Synonyms 5T4
Function May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma
Research Areas
Citations (0)
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$ 365.00
Cat# APR10069
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