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Anti-MASP2 Reference Antibody (narsoplimab)

Recombinant Antibody

     
  •  - Anti-MASP2 Reference Antibody (narsoplimab) APR10196
    Anti-MASP2 Reference Antibody (narsoplimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-MASP2 Reference Antibody (narsoplimab) APR10196
    The purity of Anti-MASP2 Reference Antibody (narsoplimab)is more than 98.94% ,determined by SEC-HPLC.
    detail
  •  - Anti-MASP2 Reference Antibody (narsoplimab) APR10196
    Immobilized human MASP 2A His at 2  µg/mL can bind Anti-MASP2 Reference Antibody (narsoplimab),EC50=0.006278 µg/mL
    detail
  •  - Anti-MASP2 Reference Antibody (narsoplimab) APR10196
    C5b-C9 of the MBL pathway can be completely inhibited by Anti-MASP2 Reference Antibody (narsoplimab) with an IC50 of 0.7337 µg/mL.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession O00187
Reactivity Rat, Cynomolgus, Human, Mouse
Clonality Monoclonal
Isotype IgG4
Calculated MW 143.1 KDa
Additional Information
Target/Specificity MASP2
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name MASP2
Function Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Cellular Location Secreted.
Tissue Location Plasma.
Research Areas
Citations (0)
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$ 365.00
Cat# APR10196
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