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Anti-ROR2 Reference Antibody (Ozuriftamab)

Recombinant Antibody

     
  •  - Anti-ROR2 Reference Antibody (Ozuriftamab) APR10208
    Anti-ROR2 Reference Antibody (Ozuriftamab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-ROR2 Reference Antibody (Ozuriftamab) APR10208
    The purity of Anti-ROR2 Reference Antibody (Ozuriftamab)is more than 99.73% ,determined by SEC-HPLC.
    detail
  •  - Anti-ROR2 Reference Antibody (Ozuriftamab) APR10208
    Immobilized human ROR2 His at 2  µg/mL can bind Anti-ROR2 Reference Antibody (Ozuriftamab),EC50=0.114 µg/mL
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession Q01974
Reactivity Cynomolgus, Human, Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 144.98 KDa
Additional Information
Target/Specificity ROR2
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name ROR2
Synonyms NTRKR2
Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)
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$ 365.00
Cat# APR10208
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