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Anti-Mesothelin Reference Antibody (anetumab)

Recombinant Antibody

     
  •  - Anti-Mesothelin Reference Antibody (anetumab) APR10231
    Anti-Mesothelin Reference Antibody (anetumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
    detail
  •  - Anti-Mesothelin Reference Antibody (anetumab) APR10231
    The purity of Anti-Mesothelin Reference Antibody (anetumab)is more than 98.58% ,determined by SEC-HPLC.
    detail
  •  - Anti-Mesothelin Reference Antibody (anetumab) APR10231
    Immobilized human Mesothelin His at 2  µg/mL can bind Anti-Mesothelin Reference Antibody (anetumab),EC50=0.01877 µg/mL
    detail
  •  - Anti-Mesothelin Reference Antibody (anetumab) APR10231
    ASPC-1 cells were stained with Anti-Mesothelin Reference Antibody (anetumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC291=0.1822 µg/mL
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession Q13421
Reactivity Human, Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 143.8 KDa
Additional Information
Target/Specificity Mesothelin
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name MSLN
Synonyms MPF
Function Membrane-anchored forms may play a role in cellular adhesion.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus [Isoform 3]: Secreted.
Tissue Location Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
Research Areas
Citations (0)
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$ 365.00
Cat# APR10231
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