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Anti-FceR2 / CD23 Reference Antibody (lumiliximab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | P06734 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 144.82 KDa |
| Target/Specificity | FceR2 / CD23 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Storage | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| Name | FCER2 |
|---|---|
| Synonyms | CD23A, CLEC4J, FCE2, IGEBF |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed:2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine- nitric oxide pathway (PubMed:7544003). |
| Cellular Location | Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23 |
| Tissue Location | Detected in urine (at protein level). |
Research Areas
Citations (0)
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Application Protocols
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$ 365.00
Cat# APR10378
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