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Anti-FGF19 Reference Antibody (1A6)

Recombinant Antibody

     
  •  - Anti-FGF19 Reference Antibody (1A6) APR10557
    Anti-FGF19 Reference Antibody (1A6) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%
    detail
  •  - Anti-FGF19 Reference Antibody (1A6) APR10557
    The purity of Anti-FGF19 Reference Antibody (1A6)is more than 95% ,determined by SEC-HPLC.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, E, FTA
Primary Accession O95750
Reactivity Cynomolgus, Human
Clonality Monoclonal
Isotype IgG1
Calculated MW 145 KDa
Additional Information
Target/Specificity FGF19
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Storage -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
Protein Information
Name FGF19
Function Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Cellular Location Secreted.
Tissue Location Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Research Areas
Citations (0)
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$ 365.00
Cat# APR10557
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