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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-SOST / Sclerostin Reference Antibody (romosozumab)
Anti-SOST / Sclerostin Reference Antibody (romosozumab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | Q9BQB4 |
| Reactivity | Cynomolgus, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2SA |
| Calculated MW | 146.32 KDa |
| Target/Specificity | SOST / Sclerostin |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Storage | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| Name | SOST (HGNC:13771) |
|---|---|
| Function | Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. |
| Cellular Location | Secreted, extracellular space, extracellular matrix |
| Tissue Location | Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
Cat# APR10572
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