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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-KIR3DL2 / CD158k Reference Antibody (lacutamab)
Anti-KIR3DL2 / CD158k Reference Antibody (lacutamab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | P43630 |
| Reactivity | Human, Mouse, Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 144.52 KDa |
| Target/Specificity | KIR3DL2 / CD158k |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Storage | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| Name | KIR3DL2 {ECO:0000303|PubMed:24018270, ECO:0000312|HGNC:HGNC:6339} |
|---|---|
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed:24018270, PubMed:28636952). Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions (PubMed:24018270). Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PubMed:26928464). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in astrocytes. |
Research Areas
Citations (0)
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Application Protocols
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$ 365.00
Cat# APR10685
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