Anti-KID3 Reference Antibody (Macrogenics patent anti-KID3)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| FC, Kinetics, Animal Model |
|---|---|
| Primary Accession | Q86Y25 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Calculated MW | 147.04 KDa |
| Target/Specificity | KID3 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | ZNF354C |
|---|---|
| Synonyms | KID3 |
| Function | Transcriptional repressor that inhibits endothelial angiogenic sprouting (PubMed:15555547, PubMed:33154469). Suppresses osteogenic effects of RUNX2 and may be involved in osteoblastic differentiation (By similarity). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity). |
| Cellular Location | Nucleus. Nucleus membrane. Cytoplasm |
| Tissue Location | Expressed in kidney and skeletal muscle. Very low expression in brain and heart (PubMed:15555547). Strongly expressed in vascular cells such as umbilical vein endothelial cells, microvascular endothelial cells and aortic smooth muscle cells (PubMed:33154469) |

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