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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-MICB Reference Antibody (U.Washington patent anti-MICB)
Anti-MICB Reference Antibody (U.Washington patent anti-MICB)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | Q29980 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2SA |
| Calculated MW | 143.66 KDa |
| Target/Specificity | MICB |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Storage | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| Name | MICB {ECO:0000312|EMBL:CAA62823.1} |
|---|---|
| Function | Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q29983}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q29983} Note=Binding to human cytomegalovirus glycoprotein UL16 causes sequestration in the endoplasmic reticulum {ECO:0000250|UniProtKB:Q29983, ECO:0000269|PubMed:12782710} |
| Tissue Location | Widely expressed with the exception of the central nervous system where it is absent. Expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon In hepatocellular carcinomas, expressed in tumor cells but not in surrounding non-cancerous tissue. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
Cat# APR10978
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