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CTRP5 Antibody

     
  • WB - CTRP5 Antibody ASC10340
    Western blot analysis of CTRP5 in caco-2 cell lysate with CTRP5 antibody at (A) 1, (B) 2, and (C) 4 µg/mL.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BXJ0
Other Accession AAQ88749, 37181891
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 25298 Da
Application Notes CTRP5 antibody can be used for the detection of CTRP5 by Western blot at 1 - 4 µg/mL.
Additional Information
Gene ID 114902
Other Names CTRP5 Antibody: CTRP5, CTRP5, UNQ303/PRO344, Complement C1q tumor necrosis factor-related protein 5, C1q and tumor necrosis factor related protein 5
Target/Specificity C1QTNF5; Adipokine proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Reconstitution & Storage CTRP5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsCTRP5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C1QTNF5
Synonyms CTRP5
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

CTRP5 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

References

CTRP5 antibody can be stored at 4˚C, stable for one year. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9.
Tsao T-S, Lodish HF, and Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Euro. J. Pharmacol. 2002; 440:213-21.
Wong GW, Wang J, Hug C, et al. A family of Acrp30/ adiponectin structural and functional paralogs. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.
Shapiro L and Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr. Biol. 1998; 8:335-8.

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$ 379.00
Cat# ASC10340
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