JMJD4 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q9H9V9 |
| Other Accession | NP_075383, 239788847 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 47425 Da |
| Application Notes | JMJD4 antibody can be used for detection of JMJD4 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 5 µg/mL. |
| Gene ID | 65094 |
|---|---|
| Target/Specificity | JMJD4; This antibody will not recognize other members of the JMJD family. |
| Reconstitution & Storage | JMJD4 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | JMJD4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | JMJD4 |
|---|---|
| Function | Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1. |
| Cellular Location | Cytoplasm. |

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Provided below are standard protocols that you may find useful for product applications.
Background
JMJD4 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the JMJD4 has not been identified. JMJD4 is expressed in multiple tissues and At least three isoforms of JMJD4 are known to exist.
References
Takeuchi T, Watanabe Y, Takano-Shimizu T, et al. Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev. Dyn.2006; 235:2449-59.
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