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INF2 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q27J81 |
| Other Accession | NP_071934 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone Names | INF2 |
| Calculated MW | Predicted: 137 kDa Observed: 160 kDa |
| Gene ID | 64423 |
|---|---|
| Alias Symbol | INF2 |
| Other Names | INF2 Antibody: FSGS5, CMTDIE, C14orf151, C14orf173 |
| Target/Specificity | INF2 Antibody is predicted to not cross-react with other INF1. |
| Reconstitution & Storage | INF2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | INF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | INF2 |
|---|---|
| Synonyms | C14orf151, C14orf173 |
| Function | Severs actin filaments and accelerates their polymerization and depolymerization. |
| Cellular Location | Cytoplasm, perinuclear region |
| Tissue Location | Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
INF2 is a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5
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