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LRP4 (Extracellular) Antibody
LRP4 Antibody, Clone S207-27
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8VI56 |
| Other Accession | NP_766256.3 |
| Host | Mouse |
| Isotype | IgG2A |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal |
| Description | Mouse Anti-Mouse LRP4 (Extracellular) Monoclonal IgG2A |
| Target/Specificity | Detects the extracellular domain of LRP4 ~215kDa. Degradation product can be seen at ~150kDa. |
| Other Names | Corin Antibody, KIAA0816 Antibody, LDLR Antibody, LDLR dan Antibody, Low density lipoprotein receptor related protein 4 Antibody, LRP-4 Antibody, LRP10 Antibody, MEGF7 Antibody, Multiple epidermal growth factor like domains 7 Antibody |
| Clone Names | S207-27 |
| Immunogen | Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4 |
| Purification | Protein G Purified |
| Storage | -20ºC |
| Storage Buffer | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Shipping Temperature | Blue Ice or 4ºC |
| Certificate of Analysis | 1 µg/ml of SMC-418 was sufficient for detection of LRP4 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Cellular Localization | Membrane |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.
References
1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353–92.
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