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Human IgM (myeloma) Fc5µ
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- BACKGROUND
| Description | HUMAN IgM (myeloma) Fc5 µ fragment |
|---|---|
| Conjugate | Unconjugated |
| Physical State | Liquid (sterile filtered) |
| Host Isotype | IgM |
| Buffer | 0.1 M Tris Chloride, 0.5 M Sodium Chloride, pH 8.0 |
| Species of Origin | Human |
| Preservative | 0.05% (w/v) Sodium Azide |
| Shipping Condition | Wet Ice |
|---|---|
| Purity | Human IgM (myeloma) Fc5 µ fragment has been prepared from Human IgM myeloma protein by digestion with trypsin followed by column chromatography. Purity was assessed by SDS-PAGE and HPLC to be greater than 95%. A single precipitin arc was observed against anti-human IgM Fc5 µ and anti-human serum when assayed by immuno-electrophoresis at a concentration of 20 mg/ml. No reaction was observed against anti-Trypsin, anti-human IgG F(ab')2, anti-human IgG F(c), anti-human Kappa or anti-human Lambda. |
| Storage Condition | Store vial at 4° C prior to opening. Human IgM (myeloma) Fc5 µ fragment is stable 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage mix with an equal volume of glycerol, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. |
| Precautions Note | This product is for research use only and is not intended for therapeutic or diagnostic applications. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Immunoglobulin M is the largest antibody isotype and the first to be secrected against an initial exposure to antigen. IgM is predominantly produced in the spleen. IgM is formed from covalently linking 5 immunoglobulins together. Due to this large size, IgM is typically isolated to the serum. Human IgM (myeloma) Fc5 µ fragment consists of only the µ (mu) chain of the Fc fragment.
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