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ADA Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ADA.

     
  • WB - ADA Antibody (monoclonal) (M01) AT1040a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (65.45 KDa) .
    detail
  • WB - ADA Antibody (monoclonal) (M01) AT1040a
    ADA monoclonal antibody (M01), clone 4G4-1C6. Western Blot analysis of ADA expression in HL-60 ( (Cat # AT1040a )
    detail
  • WB - ADA Antibody (monoclonal) (M01) AT1040a
    ADA monoclonal antibody (M01), clone 4G4-1C6. Western Blot analysis of ADA expression in Jurkat ( (Cat # AT1040a )
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  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P00813
Other Accession BC040226
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 4G4-1C6
Calculated MW 40764 Da
Additional Information
Gene ID 100
Other Names Adenosine deaminase, Adenosine aminohydrolase, ADA, ADA1
Target/Specificity ADA (AAH40226.1, 1 a.a. ~ 363 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsADA Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

References

An indication for correlation between the serum ADA level and gastric cancer risk. Ri G, et al. Anticancer Res, 2010 Jun. PMID 20651391.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Levine AJ, et al. Cancer Epidemiol Biomarkers Prev, 2010 Jul. PMID 20615890.A Study of Three Polymorphic Sites of ADA Gene in Colon Cancer. Spina C, et al. Cancer Invest, 2010 Jun 30. PMID 20590444.The interaction of ACP1, ADA1, diabetes and gender in coronary artery disease. Gloria-Bottini F, et al. Am J Med Sci, 2010 Aug. PMID 20581655.

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$ 350.00
Cat# AT1040a
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Availability: 7-10 days
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