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ADRM1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant ADRM1.

     
  • IF - ADRM1 Antibody (monoclonal) (M01) AT1060a
    Immunofluorescence of monoclonal antibody to ADRM1 on HeLa cell. [antibody concentration 10 ug/ml]
    detail
  • IP - ADRM1 Antibody (monoclonal) (M01) AT1060a
    Immunoprecipitation of ADRM1 transfected lysate using anti-ADRM1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with ADRM1 monoclonal antibody.
    detail
  • WB - ADRM1 Antibody (monoclonal) (M01) AT1060a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (68.64 KDa) .
    detail
  • WB - ADRM1 Antibody (monoclonal) (M01) AT1060a
    ADRM1 monoclonal antibody (M01), clone 3C6 Western Blot analysis of ADRM1 expression in HeLa ( (Cat # AT1060a )
    detail
  • WB - ADRM1 Antibody (monoclonal) (M01) AT1060a
    Western Blot analysis of ADRM1 expression in transfected 293T cell line by ADRM1 monoclonal antibody (M01), clone 3C6.

    Lane 1: ADRM1 transfected lysate(42.2 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - ADRM1 Antibody (monoclonal) (M01) AT1060a
    Detection limit for recombinant GST tagged ADRM1 is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, IP, E
Primary Accession Q16186
Other Accession BC017245
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 3C6
Calculated MW 42153 Da
Additional Information
Gene ID 11047
Other Names Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog, ADRM1, GP110
Target/Specificity ADRM1 (AAH17245.1, 18 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsADRM1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.

References

1.Phospho-?GNp63 ? /Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells.Huang Y, Ratovitski EA.Aging (Albany NY). 2010 Dec;2(12):959-68.2.Phosphorylated TP63 Induces Transcription of RPN13, Leading to NOS2 Protein Degradation.Huang Y, Ratovitski EA.J Biol Chem. 2010 Dec 31;285(53):41422-31. Epub 2010 Oct 19.3.Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content.Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S, Bernard L, Viale G, Pelicci PG, Di Fiore PP.Cell. 2010 Jan 8;140(1):62-73.

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$ 350.00
Cat# AT1060a
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Availability: 7-10 days
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