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AKR1C4 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant AKR1C4.

  • IF - AKR1C4 Antibody (monoclonal) (M01) AT1094a
    Immunofluorescence of monoclonal antibody to AKR1C4 on HepG2 cell. [antibody concentration 15 ug/ml]
  • WB - AKR1C4 Antibody (monoclonal) (M01) AT1094a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (61.27 KDa) .
  • WB - AKR1C4 Antibody (monoclonal) (M01) AT1094a
    AKR1C4 monoclonal antibody (M01), clone 2C11 Western Blot analysis of AKR1C4 expression in MCF-7 ( (Cat # AT1094a )
  • WB - AKR1C4 Antibody (monoclonal) (M01) AT1094a
    Western Blot analysis of AKR1C4 expression in transfected 293T cell line by AKR1C4 monoclonal antibody (M01), clone 2C11.

    Lane 1: AKR1C4 transfected lysate(37.2 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - AKR1C4 Antibody (monoclonal) (M01) AT1094a
    Immunoperoxidase of monoclonal antibody to AKR1C4 on formalin-fixed paraffin-embedded human liver tissue. [antibody concentration 3 ug/ml]
  • E - AKR1C4 Antibody (monoclonal) (M01) AT1094a
    Detection limit for recombinant GST tagged AKR1C4 is 3 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17516
Other Accession BC020744
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 2C11
Calculated MW 37067 Da
Additional Information
Gene ID 1109
Other Names Aldo-keto reductase family 1 member C4, 111-, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, CDR, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
Target/Specificity AKR1C4 (AAH20744, 1 a.a. ~ 323 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsAKR1C4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.


1.Regulation of Human 3{alpha}-Hydroxysteroid Dehydrogenase (AKR1C4) Expression by the Liver X Receptor {alpha}.Stayrook KR, Rogers PM, Savkur RS, Wang Y, Su C, Varga G, Bu X, Wei T, Nagpal S, Liu XS, Burris TP.Mol Pharmacol. 2008 Feb;73(2):607-12. Epub 2007 Nov 16.

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$ 350.00
Cat# AT1094a
Availability: 7-10 days
Bulk Size

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