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ALG6 Antibody (monoclonal) (M09)

Mouse monoclonal antibody raised against a partial recombinant ALG6.

     
  • IF - ALG6 Antibody (monoclonal) (M09) AT1121a
    Immunofluorescence of monoclonal antibody to ALG6 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - ALG6 Antibody (monoclonal) (M09) AT1121a
    ALG6 monoclonal antibody (M09), clone 2G11 Western Blot analysis of ALG6 expression in Hela S3 NE ( Cat # L013V3 ).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession Q9Y672
Other Accession NM_013339
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2G11
Calculated MW 58121 Da
Additional Information
Gene ID 29929
Other Names Dolichyl pyrophosphate Man9GlcNAc2 alpha-1, 3-glucosyltransferase, Asparagine-linked glycosylation protein 6 homolog, Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1, 3-glucosyltransferase, Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase, ALG6
Target/Specificity ALG6 (NP_037471, 25 a.a. ~ 114 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsALG6 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
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Background

This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic.

References

The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.Congenital disorder of glycosylation Ic due to a de novo deletion and an hALG-6 mutation. Eklund EA, et al. Biochem Biophys Res Commun, 2006 Jan 20. PMID 16321363.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.Identification of a frequent variant in ALG6, the cause of Congenital Disorder of Glycosylation-Ic. Westphal V, et al. Hum Mutat, 2003 Nov. PMID 14517965.

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$ 350.00
Cat# AT1121a
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