ANKRD15 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ANKRD15.
|Application ||WB, E|
|Calculated MW||147289 Da|
|Other Names||KN motif and ankyrin repeat domain-containing protein 1, Ankyrin repeat domain-containing protein 15, Kidney ankyrin repeat-containing protein, KANK1, ANKRD15, KANK, KIAA0172|
|Target/Specificity||ANKRD15 (AAH38116, 701 a.a. ~ 800 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ANKRD15 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a protein containing four ankyrin repeat domains in its C-terminus. The suggested role for this protein is in tumorigenesis of renal cell carcinoma. Two alternatively spliced transcript variants encoding different isoforms have been identified.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia. Medves S, et al. Leukemia, 2010 May. PMID 20164854.Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis. Hoppenbrouwers IA, et al. J Hum Genet, 2009 Nov. PMID 19834503.A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane. Kakinuma N, et al. Biochem Biophys Res Commun, 2009 Sep 4. PMID 19559006.Risk alleles for multiple sclerosis in multiplex families. D'Netto MJ, et al. Neurology, 2009 Jun 9. PMID 19506219.
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