ATOH7 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant ATOH7.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q8N100 |
Other Accession | NM_145178 |
Reactivity | Human |
Host | mouse |
Clonality | Monoclonal |
Isotype | IgG2a Kappa |
Clone Names | 1E6 |
Calculated MW | 16871 Da |
Gene ID | 220202 |
---|---|
Other Names | Protein atonal homolog 7, Class A basic helix-loop-helix protein 13, bHLHa13, Helix-loop-helix protein hATH-5, hATH5, ATOH7, ATH5, BHLHA13 |
Target/Specificity | ATOH7 (NP_660161, 53 a.a. ~ 99 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Dilution | WB~~1:500~1000 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | ATOH7 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ATOH7 is a member of the family of basic helix-loop-helix (bHLH) proteins with similarity to Drosophila 'atonal,' a proneural bHLH gene that controls photoreceptor development (Brown et al., 2002 [PubMed 11889557]).
References
A genome-wide association study of optic disc parameters. Ramdas WD, et al. PLoS Genet, 2010 Jun 10. PMID 20548946.Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Macgregor S, et al. Hum Mol Genet, 2010 Jul 1. PMID 20395239.Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. McLellan AS, et al. Mech Dev, 2002 Dec. PMID 14516699.Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. McLellan AS, et al. Gene Expr Patterns, 2002 Dec. PMID 12617822.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
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