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ATP2A3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ATP2A3.

     
  • WB - ATP2A3 Antibody (monoclonal) (M01) AT1234a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (38.94 KDa) .
    detail
  • WB - ATP2A3 Antibody (monoclonal) (M01) AT1234a
    ATP2A3 monoclonal antibody (M01), clone 2H3 Western Blot analysis of ATP2A3 expression in HL-60 ( (Cat # AT1234a )
    detail
  • IHC - ATP2A3 Antibody (monoclonal) (M01) AT1234a
    Immunoperoxidase of monoclonal antibody to ATP2A3 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]
    detail
  • E - ATP2A3 Antibody (monoclonal) (M01) AT1234a
    Detection limit for recombinant GST tagged ATP2A3 is approximately 0.3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q93084
Other Accession BC035729
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2H3
Calculated MW 109256 Da
Additional Information
Gene ID 489
Other Names Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, SERCA3, SR Ca(2+)-ATPase 3, Calcium pump 3, ATP2A3
Target/Specificity ATP2A3 (AAH35729, 501 a.a. ~ 620 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsATP2A3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

1.Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation.Arbabian A, Brouland JP, Apati A, Paszty K, Hegedus L, Enyedi A, Chomienne C, Papp B.FEBS J. 2012 Nov 15. doi: 10.1111/febs.12064.2.Expression of Sarco/Endoplasmic Reticulum Ca2+ATPase (SERCA) 3 proteins in two major conformational states in native human cell membranes.Corvazier E, Bredoux R, Kovacs T, Enouf J.Biochim Biophys Acta. 2009 Mar;1788(3):587-99. Epub 2008 Dec 16.

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$ 350.00
Cat# AT1234a
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