CHRAC1 Antibody (monoclonal) (M11)
Mouse monoclonal antibody raised against a partial recombinant CHRAC1.
|Calculated MW||14711 Da|
|Other Names||Chromatin accessibility complex protein 1, CHRAC-1, Chromatin accessibility complex 15 kDa protein, CHRAC-15, HuCHRAC15, DNA polymerase epsilon subunit p15, CHRAC1, CHRAC15|
|Target/Specificity||CHRAC1 (NP_059140, 1 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CHRAC1 Antibody (monoclonal) (M11) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. Collins N, et al. Nat Genet, 2002 Dec. PMID 12434153.
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