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>   home   >   Products   >   Primary Antibodies   >   CITED1 Antibody (monoclonal) (M03)   

CITED1 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant CITED1.

     
  • WB - CITED1 Antibody (monoclonal) (M03) AT1541a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - CITED1 Antibody (monoclonal) (M03) AT1541a
    CITED1 monoclonal antibody (M03), clone 5H6 Western Blot analysis of CITED1 expression in A-431 ( (Cat # AT1541a )
    detail
  • WB - CITED1 Antibody (monoclonal) (M03) AT1541a
    Western Blot analysis of CITED1 expression in transfected 293T cell line by CITED1 monoclonal antibody (M03), clone 5H6.

    Lane 1: CITED1 transfected lysate(19.9 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - CITED1 Antibody (monoclonal) (M03) AT1541a
    Immunoperoxidase of monoclonal antibody to CITED1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.2 ug/ml]
    detail
  • E - CITED1 Antibody (monoclonal) (M03) AT1541a
    Detection limit for recombinant GST tagged CITED1 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q99966
Other Accession NM_004143
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 5H6
Calculated MW 19896 Da
Additional Information
Gene ID 4435
Other Names Cbp/p300-interacting transactivator 1, Melanocyte-specific protein 1, CITED1, MSG1
Target/Specificity CITED1 (NP_004134, 94 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCITED1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)
citation

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Background

This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described.

References

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Dillon RL, et al. Mol Cell Biol, 2007 Dec. PMID 17938205.CITED1 expression in Wilms' tumor and embryonic kidney. Lovvorn HN, et al. Neoplasia, 2007 Jul. PMID 17710162.Wilms' tumorigenesis is altered by misexpression of the transcriptional co-activator, CITED1. Lovvorn HN 3rd, et al. J Pediatr Surg, 2007 Mar. PMID 17336183.The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner. Shi G, et al. J Biol Chem, 2006 Sep 15. PMID 16864582.Cited1 is a bifunctional transcriptional cofactor that regulates early nephronic patterning. Plisov S, et al. J Am Soc Nephrol, 2005 Jun. PMID 15843474.

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$ 350.00
Cat# AT1541a
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Availability: 7-10 days
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