COPl Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant COPl.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q5EG05 |
| Other Accession | NM_052889 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3E11 |
| Calculated MW | 22625 Da |
| Gene ID | 114769 |
|---|---|
| Other Names | Caspase recruitment domain-containing protein 16, Caspase recruitment domain-only protein 1, CARD-only protein 1, Caspase-1 inhibitor COP, Pseudo interleukin-1 beta converting enzyme, Pseudo-ICE, Pseudo-IL1B-converting enzyme, CARD16, COP, COP1 |
| Target/Specificity | COPl (NP_443121, 1 a.a. ~ 97 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | COPl Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |

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References
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death. Wang X, et al. Biochim Biophys Acta, 2006 Aug. PMID 16920334.Dysregulation of receptor interacting protein-2 and caspase recruitment domain only protein mediates aberrant caspase-1 activation in Huntington's disease. Wang X, et al. J Neurosci, 2005 Dec 14. PMID 16354923.INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation. Lamkanfi M, et al. J Biol Chem, 2004 Dec 10. PMID 15383541.
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