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CPSF6 Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant CPSF6.

     
  • IF - CPSF6 Antibody (monoclonal) (M07) AT1612a
    Immunofluorescence of monoclonal antibody to CPSF6 on HeLa cell . [antibody concentration 10 ug/ml]
    detail
  • WB - CPSF6 Antibody (monoclonal) (M07) AT1612a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - CPSF6 Antibody (monoclonal) (M07) AT1612a
    CPSF6 monoclonal antibody (M07), clone 1C5. Western Blot analysis of CPSF6 expression in NIH/3T3 ( (Cat # AT1612a )
    detail
  • E - CPSF6 Antibody (monoclonal) (M07) AT1612a
    Detection limit for recombinant GST tagged CPSF6 is 0.3 ng/ml as a capture antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q16630
Other Accession NM_007007
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG2b Kappa
Clone Names 1C5
Calculated MW 59210 Da
Additional Information
Gene ID 11052
Other Names Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68 kDa subunit, CFIm68, CPSF 68 kDa subunit, Pre-mRNA cleavage factor Im 68 kDa subunit, Protein HPBRII-4/7, CPSF6, CFIM68
Target/Specificity CPSF6 (NP_008938, 37 a.a. ~ 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCPSF6 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
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Background

The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

References

Flexible use of nuclear import pathways by HIV-1. Lee K, et al. Cell Host Microbe, 2010 Mar 18. PMID 20227665.Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export. Ruepp MD, et al. Mol Biol Cell, 2009 Dec. PMID 19864460.Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967.Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. Maggi LB Jr, et al. Mol Cell Biol, 2008 Dec. PMID 18809582.Many sequence variants affecting diversity of adult human height. Gudbjartsson DF, et al. Nat Genet, 2008 May. PMID 18391951.

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$ 350.00
Cat# AT1612a
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