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DNMBP Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant DNMBP.

     
  • WB - DNMBP Antibody (monoclonal) (M03) AT1804a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
    detail
  • WB - DNMBP Antibody (monoclonal) (M03) AT1804a
    Western Blot analysis of DNMBP expression in transfected 293T cell line by DNMBP monoclonal antibody (M03), clone 3H7.

    Lane 1: DNMBP transfected lysate(93.6 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q6XZF7
Other Accession BC041628
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG3 Kappa
Clone Names 3H7
Calculated MW 177347 Da
Additional Information
Gene ID 23268
Other Names Dynamin-binding protein, Scaffold protein Tuba, DNMBP, KIAA1010
Target/Specificity DNMBP (AAH41628, 491 a.a. ~ 590 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsDNMBP Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

DNMBP belongs to the DBL (MIM 311030) family of guanine nucleotide exchange factors and plays a role in the regulation of cell junctions (Otani et al., 2006 [PubMed 17015620]).

References

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. Voss M, et al. BMC Immunol, 2009 Oct 6. PMID 19807924.Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. Thalappilly S, et al. Proteomics, 2008 Aug. PMID 18654987.Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. Morgan AR, et al. Am J Med Genet B Neuropsychiatr Genet, 2009 Jan 5. PMID 18452187.DNMBP is genetically associated with Alzheimer dementia in the Belgian population. Bettens K, et al. Neurobiol Aging, 2009 Dec. PMID 18359537.No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease. Minster RL, et al. Neurobiol Aging, 2008 Oct. PMID 17442457.

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$ 350.00
Cat# AT1804a
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Availability: 7-10 days
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