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EMILIN1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant EMILIN1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y6C2 |
| Other Accession | BC007530 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 4A3 |
| Calculated MW | 106695 Da |
| Gene ID | 11117 |
|---|---|
| Other Names | EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1, EMILIN1, EMI |
| Target/Specificity | EMILIN1 (AAH07530, 1 a.a. ~ 347 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | EMILIN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung.
References
Association study of the elastin microfibril interfacer 1 (EMILIN1) gene in essential hypertension. Shimodaira M, et al. Am J Hypertens, 2010 May. PMID 20186130.Emilin1 gene and essential hypertension: a two-stage association study in northern Han Chinese population. Shen C, et al. BMC Med Genet, 2009 Nov 18. PMID 19922630.NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1. Verdone G, et al. J Biomol NMR, 2009 Feb. PMID 19023665.Candidate gene analysis in primary lymphedema. Ferrell RE, et al. Lymphat Res Biol, 2008. PMID 18564921.The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin. Verdone G, et al. J Biol Chem, 2008 Jul 4. PMID 18463100.
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