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FOXC2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant FOXC2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | Q99958 |
| Other Accession | NM_005251 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Lambda |
| Clone Names | 2H3 |
| Calculated MW | 53719 Da |
| Gene ID | 2303 |
|---|---|
| Other Names | Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14, FOXC2, FKHL14, MFH1 |
| Target/Specificity | FOXC2 (NP_005242.1, 421 a.a. ~ 501 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | FOXC2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
References
1.MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol.Yu YH, Chen HA, Chen PS, Cheng YJ, Hsu WH, Chang YW, Chen YH, Jan Y, Hsiao M, Chang TY, Liu YH, Jeng YM, Wu CH, Huang MT, Su YH, Hung MC, Chien MH, Chen CY, Kuo ML, Su JL.Oncogene. 2012 Mar 12. doi: 10.1038/onc.2012.74. [Epub ahead of print]2.FOXC2 is a Novel Prognostic Factor in Human Esophageal Squamous Cell Carcinoma.Nishida N, Mimori K, Yokobori T, Sudo T, Tanaka F, Shibata K, Ishii H, Doki Y, Mori M.Ann Surg Oncol. 2010 Aug 28. [Epub ahead of print]
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