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FOXC2 Antibody (monoclonal) (M03)

Mouse monoclonal antibody raised against a partial recombinant FOXC2.

     
  • WB - FOXC2 Antibody (monoclonal) (M03) AT2089a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.65 KDa) .
    detail
  • WB - FOXC2 Antibody (monoclonal) (M03) AT2089a
    FOXC2 monoclonal antibody (M03), clone 4B3 Western Blot analysis of FOXC2 expression in SJCRH30 ( (Cat # AT2089a )
    detail
  • E - FOXC2 Antibody (monoclonal) (M03) AT2089a
    Detection limit for recombinant GST tagged FOXC2 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99958
Other Accession NM_005251
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4B3
Calculated MW 53719 Da
Additional Information
Gene ID 2303
Other Names Forkhead box protein C2, Forkhead-related protein FKHL14, Mesenchyme fork head protein 1, MFH-1 protein, Transcription factor FKH-14, FOXC2, FKHL14, MFH1
Target/Specificity FOXC2 (NP_005242.1, 421 a.a. ~ 501 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFOXC2 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.

References

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.A novel missense mutation and two microrearrangements in the FOXC2 gene of three families with lymphedema-distichiasis syndrome. Fauret AL, et al. Lymphology, 2010 Mar. PMID 20552815.Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population. Pappa KI, et al. Gynecol Endocrinol, 2010 Jun 14. PMID 20540670.A case of lymphedema-distichiasis syndrome carrying a new de novo frameshift FOXC2 mutation. Fabretto A, et al. Ophthalmic Genet, 2010 Jun. PMID 20450314.Lymphedema-distichiasis syndrome without FOXC2 mutation: evidence for chromosome 16 duplication upstream of FOXC2. Witte MH, et al. Lymphology, 2009 Dec. PMID 20218083.

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$ 350.00
Cat# AT2089a
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Availability: 7-10 days
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