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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Anti-Wnt-Pathway (plus Lgr5) Antibodies   >   GNG3 Antibody (monoclonal) (M01)   

GNG3 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant GNG3.

     
  • WB - GNG3 Antibody (monoclonal) (M01) AT2230a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (33.99 KDa) .
    detail
  • WB - GNG3 Antibody (monoclonal) (M01) AT2230a
    GNG3 monoclonal antibody (M01), clone 1E10-1B5. Western Blot analysis of GNG3 expression in rat brain.
    detail
  • E - GNG3 Antibody (monoclonal) (M01) AT2230a
    Detection limit for recombinant GST tagged GNG3 is approximately 1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P63215
Other Accession BC015563
Reactivity Human, Rat
Host mouse
Clonality Monoclonal
Isotype IgG2b kappa
Clone Names 1E10-1B5
Calculated MW 8305 Da
Additional Information
Gene ID 2785
Other Names Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3, GNG3, GNGT3
Target/Specificity GNG3 (AAH15563, 1 a.a. ~ 75 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGNG3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

G proteins are heterotrimers of alpha, beta, and gamma subunits. Gamma subunits, such as GNG3, contribute to the specificity of the hundreds of receptor signaling pathways involving G proteins (Schwindinger et al., 2004 [PubMed 15314181]).

References

Regulation of Golgi structure and secretion by receptor-induced G protein betagamma complex translocation. Saini DK, et al. Proc Natl Acad Sci U S A, 2010 Jun 22. PMID 20534534.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Mice with deficiency of G protein gamma3 are lean and have seizures. Schwindinger WF, et al. Mol Cell Biol, 2004 Sep. PMID 15314181.Characterization of heterotrimeric G protein complexes in rice plasma membrane. Kato C, et al. Plant J, 2004 Apr. PMID 15078334.Glucagon and regulation of glucose metabolism. Jiang G, et al. Am J Physiol Endocrinol Metab, 2003 Apr. PMID 12626323.

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$ 350.00
Cat# AT2230a
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