HOXA7 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant HOXA7.
|Application ||WB, E|
|Calculated MW||25355 Da|
|Other Names||Homeobox protein Hox-A7, Homeobox protein Hox 11, Homeobox protein Hox-1A, HOXA7, HOX1A|
|Target/Specificity||HOXA7 (NP_008827, 58 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HOXA7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.
1.HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells.Chung N, Jee BK, Chae SW, Jeon YW, Lee KH, Rha HK.Mol Biol Rep. 2009 Feb;36(2):227-35. Epub 2007 Oct 30.
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