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HOXC13 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant HOXC13.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P31276 |
| Other Accession | NM_017410 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 10D4 |
| Calculated MW | 35379 Da |
| Gene ID | 3229 |
|---|---|
| Other Names | Homeobox protein Hox-C13, Homeobox protein Hox-3G, HOXC13, HOX3G |
| Target/Specificity | HOXC13 (NP_059106, 132 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | HOXC13 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.
References
1.Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation.Mill P, Lee AW, Fukata Y, Tsutsumi R, Fukata M, Keighren M, Porter RM, McKie L, Smyth I, Jackson IJ.PLoS Genet. 2009 Nov;5(11):e1000748. Epub 2009 Nov 26.2.Dlx3 is a crucial regulator of hair follicle differentiation and cycling.Hwang J, Mehrani T, Millar SE, Morasso MI.Development. 2008 Sep;135(18):3149-59. Epub 2008 Aug 6.
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