HRASLS3 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant HRASLS3.
|Calculated MW||17937 Da|
|Other Names||HRAS-like suppressor 3, HRSL3, Adipose-specific phospholipase A2, AdPLA, Group XVI phospholipase A1/A2, H-rev 107 protein homolog, HRAS-like suppressor 1, HREV107-1, HREV107-3, Renal carcinoma antigen NY-REN-65, PLA2G16, HRASLS3, HREV107|
|Target/Specificity||HRASLS3 (AAH01387, 1 a.a. ~ 162 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HRASLS3 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes. Uyama T, et al. Biochim Biophys Acta, 2009 Dec. PMID 19615464.AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Jaworski K, et al. Nat Med, 2009 Feb. PMID 19136964.Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). Duncan RE, et al. J Biol Chem, 2008 Sep 12. PMID 18614531.Mechanisms of the HRSL3 tumor suppressor function in ovarian carcinoma cells. Nazarenko I, et al. J Cell Sci, 2007 Apr 15. PMID 17374643.H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling. Nazarenko I, et al. Am J Pathol, 2006 Oct. PMID 17003497.
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