IL20 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant IL20.
|Application ||WB, IP, E|
|Calculated MW||20072 Da|
|Other Names||Interleukin-20, IL-20, Cytokine Zcyto10, IL20, ZCYTO10|
|Target/Specificity||IL20 (NP_061194, 67 a.a. ~ 176 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||IL20 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. PMID 20503287.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.IL-24 transgenic mice: in vivo evidence of overlapping functions for IL-20, IL-22, and IL-24 in the epidermis. He M, et al. J Immunol, 2010 Feb 15. PMID 20061404.The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Wolk K, et al. Eur J Immunol, 2009 Dec. PMID 19830738.Cytokine expression and signaling in drug-induced cellular senescence. Novakova Z, et al. Oncogene, 2010 Jan 14. PMID 19802007.
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