Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
ITGB7 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant ITGB7.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF |
|---|---|
| Primary Accession | P26010 |
| Other Accession | NM_000889 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 8D3 |
| Calculated MW | 86903 Da |
| Gene ID | 3695 |
|---|---|
| Other Names | Integrin beta-7, Gut homing receptor beta subunit, ITGB7 |
| Target/Specificity | ITGB7 (NP_000880, 401 a.a. ~ 505 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | ITGB7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1. Cicala C, et al. Proc Natl Acad Sci U S A, 2009 Dec 8. PMID 19933330.The regulation mechanism for the auto-inhibition of binding of human filamin A to integrin. Pentik?inen U, et al. J Mol Biol, 2009 Oct 30. PMID 19699211.Structural basis of the migfilin-filamin interaction and competition with integrin beta tails. Lad Y, et al. J Biol Chem, 2008 Dec 12. PMID 18829455.AhR- and c-maf-dependent induction of beta7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons. Monteiro P, et al. Biochem Biophys Res Commun, 2007 Jun 29. PMID 17490615.Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis. Le Floc'h A, et al. J Exp Med, 2007 Mar 19. PMID 17325197.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
